Composition: Cabergoline
Form: Tablets
Indications: Prevention and suppression of physiological lactation after childbirth; treatment of hyperprolactinemia (amenorrhea, oligomenorrhea, anovulation, galactorrhea); prolactin-secreting pituitary adenomas (micro- and macroprolactinomas); idiopathic hyperprolactinemia; hyperprolactinemia in empty sella syndrome.
Contraindications: Hypersensitivity to cabergoline or other ergot alkaloids; fibrotic disorders or their history (valvular fibrosis, pleuropericardial or retroperitoneal fibrosis); heart valve defects confirmed by echocardiography; age under 16; lactose intolerance, lactase deficiency or glucose-galactose malabsorption.
Dosage: Orally with food. For lactation suppression: 1 mg (2 tablets) once after delivery. To suppress established lactation: 0.25 mg twice a day (every 12 h) for 2 days (total dose 1 mg); single dose should not exceed 0.25 mg. For hyperprolactinemia: start with 0.5 mg once a week, increase monthly by 0.5 mg if needed (usually 1 mg/week; range 0.25–2 mg/week; max 4.5 mg/week). Tablet may be taken once weekly or split into two doses.
Side effects: Dizziness, headache, fatigue, drowsiness, depression, asthenia, paresthesia, fainting, nervousness, anxiety, insomnia, concentration problems; nausea, vomiting, epigastric pain, abdominal pain, constipation, dyspepsia, dry mouth, diarrhea, flatulence; palpitations, hypotension, orthostatic hypotension; mastodynia, dysmenorrhea, nosebleeds, rhinitis, hot flashes, temporary hemianopsia, vascular spasms, muscle cramps, visual impairment, flu-like symptoms, lethargy, orbital or peripheral edema, anorexia, acne, joint pain. Postmarketing: alopecia, elevated CPK, mania, dyspnea, edema, fibrosis, liver dysfunction, valvulopathy, pathological gambling, hypersexuality, aggression, psychiatric disorders, pericarditis, sudden sleep onset, weight changes, nasal congestion.
Interactions: Not recommended with dopamine antagonists (phenothiazines, butyrophenones, thioxanthenes, metoclopramide) or macrolides (erythromycin). Avoid prolonged use with other ergot alkaloids and antihypertensives.
Warnings: Before starting and every 6–12 months, conduct echocardiography to assess heart valves. Discontinue in case of fibrosis symptoms (pleura, pericardium, retroperitoneum) or valve issues. May cause orthostatic hypotension and sudden sleep onset. Use in pregnancy/lactation only if absolutely necessary under medical supervision.
Age restrictions: 16+
Pregnancy: Contraindicated during pregnancy and lactation; use only if absolutely necessary and under doctor supervision.
Country of origin: South Korea
Manufacturer: Dongkoo Bio&Pharma Co., Ltd.
Storage conditions: Store at 1–30°C in a sealed container out of reach of children. Do not freeze.
There are no studies available.
❓ How to suppress lactation quickly?
💬 Take 1 mg (2 tablets) once immediately after childbirth to stop lactation quickly.
❓ How often to take it for hyperprolactinemia?
💬 Usually 0.5 mg once a week; if needed, increase to 1–2 mg/week; maximum — 4.5 mg/week.
