
Composition: Thiamine hydrochloride, Pyridoxine hydrochloride, Cyanocobalamin, Lidocaine hydrochloride
Form: Solution for intramuscular injection (2 ml)
Indications: Neuropathies and polyneuropathies (including diabetic, alcoholic, and others); neuritis (including retrobulbar); peripheral paresis (including facial nerve); neuralgia (trigeminal and intercostal nerves); pain syndrome (radiculopathies, myalgias); nocturnal cramps; plexopathies, ganglionitis; neurological manifestations of spinal osteochondrosis (radiculopathy, lumbosciatica) for pain and inflammation relief.
Contraindications: Hypersensitivity to components; decompensated chronic heart failure; pediatric age (safety data not available).
Dosage: Deep intramuscular injection of 2 ml once daily for 5–10 days, then as indicated 2–3 times a week for 2–3 weeks. If needed, switch to oral B vitamins.
Side effects: Allergic reactions (rash, itching, angioedema), rarely — tachycardia, excessive sweating.
Interactions: Thiamine is destroyed in solutions with sulfites and alkaline media; pyridoxine should not be used simultaneously with levodopa; lidocaine enhances the effect of adrenergic agents.
Warnings: Do not administer intravenously. Use during pregnancy and lactation is not recommended.
Age restrictions: From 18 years old
Pregnancy: Not recommended during pregnancy and lactation.
Country of origin: Russia
Manufacturer: Sotex
Storage conditions: Store at 2–8°C in a place protected from light; do not freeze.
Voronezh State Medical Academy named after N.N. Burdenko, 2011
Авторы: S.P. Markin
ReadModern Rheumatology, 2010
Авторы: T.A. Vygovskaya
ReadOutpatient Doctor’s Reference Guide, 2010
Авторы: P.R. Kamchatnov
Read❓ Can the course be repeated?
💬 Yes, if necessary, repeat courses can be conducted after a break as prescribed by a doctor.
❓ How to reduce pain during injection?
💬 Inject deeply into the muscle; the solution can be slightly warmed to body temperature.