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Kompligam B 1Kompligam B 2

Kompligam B

Composition: 1 ampoule (2 ml) contains: Active ingredients: thiamine hydrochloride 100 mg, pyridoxine hydrochloride 100 mg, cyanocobalamin 1 mg, lidocaine hydrochloride 20 mg. Excipients: benzyl alcohol, sodium polyphosphate, sodium tripolyphosphate, potassium hexacyanoferrate, sodium hydroxide 1 M solution, water for injections.

Form: Solution for intramuscular injection (2 ml)

Indications: As a pathogenetic and symptomatic treatment for nervous system diseases and syndromes of various origins: • Neuropathies and polyneuropathies (diabetic, alcoholic and others). • Neuritis and polyneuritis, including retrobulbar neuritis. • Peripheral paresis, including facial nerve paresis. • Neuralgia, including trigeminal and intercostal neuralgia. • Pain syndromes (radicular pain, myalgia). • Nocturnal muscle cramps, especially in older people. • Plexopathies and ganglionitis, including herpes zoster. • Neurological manifestations of spinal osteochondrosis (radiculopathy, lumboischialgia, muscular-tonic syndromes).

Contraindications: • Hypersensitivity to any component. • Severe and acute forms of decompensated chronic heart failure. • Childhood, due to lack of studies.

Dosage: For pronounced pain, it is advisable to start with deep intramuscular administration of 2 ml daily for 5–10 days, subsequently switching either to oral treatment or to less frequent injections (2–3 times weekly for 2–3 weeks).

Side effects: Allergic reactions (rash, itching, angioedema), rarely — tachycardia, excessive sweating.

Interactions: Thiamine is destroyed in solutions with sulfites and alkaline media; pyridoxine should not be used simultaneously with levodopa; lidocaine enhances the effect of adrenergic agents.

Warnings: Do not administer intravenously. Use during pregnancy and lactation is not recommended.

Age restrictions: From 18 years old

Pregnancy: Not recommended during pregnancy and lactation.

Country of origin: Russia

Manufacturer: Sotex

Storage conditions: Store at 2–8°C in a place protected from light; do not freeze.

Clinical studies:

Neurological manifestations of diabetes mellitus

Voronezh State Medical Academy named after N.N. Burdenko, 2011

Authors: S.P. Markin

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Combined therapy with Amelotex and Kompligam B in patients with osteoarthritis

Modern Rheumatology, 2010

Authors: T.A. Vygovskaya

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Back pain — possibility of using B vitamins in complex therapy

Outpatient Doctor’s Reference Guide, 2010

Authors: P.R. Kamchatnov

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