Sustagard Arthro

Composition: Ampoule A. One ampoule (2 ml) contains: Active ingredients: glucosamine sulphate sodium chloride, calculated as dry substance, 502.5 mg (containing glucosamine sulphate 400 mg and sodium chloride 102.5 mg). Excipients: lidocaine hydrochloride, sodium disulphite, concentrated hydrochloric acid, water for injections. Ampoule B (solvent). One ampoule (1 ml) contains: diethanolamine 24.0 mg, water for injections.

Form: Concentrate for solution for intramuscular administration.

Indications: Primary and secondary osteoarthritis, osteochondrosis, spondyloarthrosis.

Contraindications: Hypersensitivity to glucosamine, lidocaine or other components of Sustagard Artro. Due to lidocaine content: cardiac conduction disorders, acute heart failure, history of epileptiform seizures, severe hepatic or renal impairment; pregnancy and breastfeeding; children and adolescents under 18. Use with caution in chronic heart failure and arterial hypotension. Seafood intolerance (shrimp, shellfish) increases the likelihood of allergic reactions. The safety of lidocaine-group anaesthetics is uncertain in patients prone to malignant hyperthermia; avoid their use in these cases. Particular caution is needed in circulatory failure, arterial hypotension, hepatic and/or renal impairment. Prescribe lidocaine cautiously in elderly patients, epilepsy, cardiac conduction disorders and respiratory failure.

Dosage: For intramuscular use only! Not for intravenous administration. Immediately before administration, mix the contents of ampoule A and ampoule B (solvent) in one syringe. Administer the prepared solution (3 ml) intramuscularly 3 times weekly for 4–6 weeks. The injections may be combined with oral glucosamine.

Side effects: Flatulence, diarrhea, constipation, urticaria, itching, burning at injection site. Possible lidocaine reactions: nausea, dizziness, tongue numbness, drowsiness, allergy, heart conduction issues.

Interactions: Compatible with NSAIDs, paracetamol, corticosteroids. Lidocaine interacts with cimetidine, beta-blockers, antiarrhythmics, TCAs, phenytoin, sedatives, and neuromuscular agents. Alcohol enhances lidocaine depression.

Warnings: Skin sensitivity test required before use. Use with caution in cardiovascular diseases, bronchial asthma, glucose intolerance. Avoid driving and operating machinery during therapy.

Age restrictions: From 18 years

Pregnancy: Contraindicated during pregnancy and breastfeeding.

Country of origin: Russia

Manufacturer: Sotex

Storage conditions: Store below 25 °C, protected from light. Keep out of children’s reach.